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Example Input Mode:
Partner Data
CBIS
Matrix
Example Data Type:
Secondary Screen (Kd)
Primary Screen(% control or competition)
If the input file contains Primary and Secondary Data, use:
Primary
Secondary
Assay Data File:
.txt or .csv format - download examples:
Bromodomain
Kd
Primary
To highlight spots, select a compound(s), click 'fill' and select entries.
Create Images for:
SB-203580
Highlight These Spots (
fill
):
SB-203580|ACVR1B|3000
SB-203580|ADCK4|3100
SB-203580|BMPR1B|3300
SB-203580|BRAF|710
SB-203580|BRK|3900
SB-203580|CIT|420
SB-203580|CSNK1A1|75
SB-203580|CSNK1A1L|1700
SB-203580|CSNK1D|37
SB-203580|CSNK1E|100
SB-203580|DDR1|1000
SB-203580|DDR2|5000
SB-203580|DMPK2|400
SB-203580|EGFR|1700
SB-203580|EPHA6|1200
SB-203580|EPHB6|3100
SB-203580|ERBB4|4800
SB-203580|FRK|1800
SB-203580|GAK|19
SB-203580|GSK3B|1700
SB-203580|JNK1|1100
SB-203580|JNK2|130
SB-203580|JNK3|35
SB-203580|LCK|2800
SB-203580|MAP4K4|3700
SB-203580|MEK2|9600
SB-203580|MEK5|1400
SB-203580|MRCKA|6200
SB-203580|MRCKB|2700
SB-203580|NLK|25
SB-203580|p38-alpha|12
SB-203580|p38-beta|70
SB-203580|p38-gamma|1500
SB-203580|PIP5K1C|2600
SB-203580|QSK|3900
SB-203580|RAF1|980
SB-203580|RIPK2|24
SB-203580|RSK1(Kin.Dom.2-C-terminal)|320
SB-203580|RSK4(Kin.Dom.2-C-terminal)|250
SB-203580|SLK|3700
SB-203580|SRC|5300
SB-203580|STK36|1300
SB-203580|TGFBR1|7100
SB-203580|TGFBR2|1800
SB-203580|TNIK|820
SB-203580|TNNI3K|3500
SB-203580|TTK|2500
SB-203580|TXK|4500
SB-203580|TYK2(JH2domain-pseudokinase)|2000
SB-203580|YANK1|1300
SB-203580|YANK2|2100
SB-203580|ZAK|4400
SB-203580|ACVR1B
SB-203580|ADCK4
SB-203580|BMPR1B
SB-203580|BRAF
SB-203580|BRK
SB-203580|CIT
SB-203580|CSNK1A1
SB-203580|CSNK1A1L
SB-203580|CSNK1D
SB-203580|CSNK1E
SB-203580|DDR1
SB-203580|DDR2
SB-203580|DMPK2
SB-203580|EGFR
SB-203580|EPHA6
SB-203580|EPHB6
SB-203580|ERBB4
SB-203580|FRK
SB-203580|GAK
SB-203580|GSK3B
SB-203580|JNK1
SB-203580|JNK2
SB-203580|JNK3
SB-203580|LCK
SB-203580|MAP4K4
SB-203580|MEK2
SB-203580|MEK5
SB-203580|MRCKA
SB-203580|MRCKB
SB-203580|NLK
SB-203580|p38-alpha
SB-203580|p38-beta
SB-203580|p38-gamma
SB-203580|PIP5K1C
SB-203580|QSK
SB-203580|RAF1
SB-203580|RIPK2
SB-203580|RSK1(Kin.Dom.2-C-terminal)
SB-203580|RSK4(Kin.Dom.2-C-terminal)
SB-203580|SLK
SB-203580|SRC
SB-203580|STK36
SB-203580|TGFBR1
SB-203580|TGFBR2
SB-203580|TNIK
SB-203580|TNNI3K
SB-203580|TTK
SB-203580|TXK
SB-203580|TYK2(JH2domain-pseudokinase)
SB-203580|YANK1
SB-203580|YANK2
SB-203580|ZAK
SB-203580|ACVR1B|3000
SB-203580|ADCK4|3100
SB-203580|BMPR1B|3300
SB-203580|BRAF|710
SB-203580|BRK|3900
SB-203580|CIT|420
SB-203580|CSNK1A1|75
SB-203580|CSNK1A1L|1700
SB-203580|CSNK1D|37
SB-203580|CSNK1E|100
SB-203580|DDR1|1000
SB-203580|DDR2|5000
SB-203580|DMPK2|400
SB-203580|EGFR|1700
SB-203580|EPHA6|1200
SB-203580|EPHB6|3100
SB-203580|ERBB4|4800
SB-203580|FRK|1800
SB-203580|GAK|19
SB-203580|GSK3B|1700
SB-203580|JNK1|1100
SB-203580|JNK2|130
SB-203580|JNK3|35
SB-203580|LCK|2800
SB-203580|MAP4K4|3700
SB-203580|MEK2|9600
SB-203580|MEK5|1400
SB-203580|MRCKA|6200
SB-203580|MRCKB|2700
SB-203580|NLK|25
SB-203580|p38-alpha|12
SB-203580|p38-beta|70
SB-203580|p38-gamma|1500
SB-203580|PIP5K1C|2600
SB-203580|QSK|3900
SB-203580|RAF1|980
SB-203580|RIPK2|24
SB-203580|RSK1(Kin.Dom.2-C-terminal)|320
SB-203580|RSK4(Kin.Dom.2-C-terminal)|250
SB-203580|SLK|3700
SB-203580|SRC|5300
SB-203580|STK36|1300
SB-203580|TGFBR1|7100
SB-203580|TGFBR2|1800
SB-203580|TNIK|820
SB-203580|TNNI3K|3500
SB-203580|TTK|2500
SB-203580|TXK|4500
SB-203580|TYK2(JH2domain-pseudokinase)|2000
SB-203580|YANK1|1300
SB-203580|YANK2|2100
SB-203580|ZAK|4400
clear
Select Highlight spots color from Pallette:
(also used in table view)
Tree Image Options
Restore default options
Spot options:
IndianRed
PaleGreen
Gold
PowderBlue
Fill?
Outline?
Outline thickness:
1
2
3
4
5
Select Spots Color from Pallette:
(spot highlight color below)
micro
nano
Spot Size:
Scaling Factor:
.1
.2
.3
.4
.5
.6
.7
.8
.9
1
1.1
1.2
1.3
Area increase factor:
100%
90%
80%
70%
60%
50%
(per change of 10x Kd or 10% Competition)
Legend options:
Left align Text
Right align Text
Label options:
Compound Name?
Compound Name Font:
.5
1
1.5
2
Show Assay Panel information?
Show Panel Spots?
Append Concentration? (i.e., 'AB500@1000nm'; check before loading.)
Background Image:
Target labels?
Dark Tree Branch image?
Hide Lipid, Mutant, ATypical and Pathogen?
Spot options:
Spot Color transparency level:
none
low
medium-low
medium
high
no color
Spot Cutoff Value:
Kd (nM) (Blank for no cutoff)
Spot outline only?
Format:
JPEG(200KB per image)
Publication Quality(5MB image)
Create Publication Quality (5MB bitmap) Image for:
Select Compound
SB-203580
size/quality
100
90
80
70
60
50
40
30
% of original
White Space Border:
Yes
No
Preview and Highlighting
Highlight an assay by clicking on the spot or checking the box next to the Gene Symbol Name.
Click 'Update' to create the new images.
Compound To Highlight:
None
SB-203580
Highlight Panel?
* WildType kinase assays appear in both the main TREEspot and Mutant kinase dendrogams.
Human Kinome image created by KINOMEscan.
2 images created. To download (copy and paste) all images to your local machine click Open/Browse Image Folder.
Images Saved To:
D:\Eurofins\PROD\Applications\FrontOffice_Discovery\StudyManagement\TreeSpot\HTSTools\TreeImages\649_4o5g4mevl0rbeggjnbejscar\
Open/Browse Image Folder
View Options:
(These options do not modify the images that have been created, only the view on this page)
SB-203580
Legend
Show Selected
Size:
Select Size
small
medium
full size
Images per Row:
1
Legend Resize?
Hover the cursor to identify spots and click to highlighted it. To save an image click the Zoom/Download link.
Zoom/Download
Highlight
Locate an Assay
BRAF
BRAF
CIT
CSNK1A1
CSNK1A1L
CSNK1D
CSNK1E
DDR1
DMPK2
EGFR
EGFR
EPHA6
FRK
GAK
GSK3B
JNK1
JNK2
JNK3
LCK
MEK5
MRCKB
NLK
p38-alpha
p38-beta
p38-gamma
PIP5K1C
RAF1
RIPK2
RSK1(Kin.Dom.2-C-terminal)
RSK4(Kin.Dom.2-C-terminal)
STK36
TGFBR2
TNIK
TTK
TYK2(JH2domain-pseudokinase)
YANK1
YANK2
Legend
Data Table View:
Show All Data
Only Selected Compounds/Trees
TREE
spot
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